Biography
Amy Marie Madigan (born September 11, 1950) is an American actress. She has acted on stage and screen, and has received a Golden Globe Award, as well as nominations for an Academy Award and an Emmy Award. She has been married to actor Ed Harris since 1983.
Madigan made her film debut in the drama Love Child (1982), for which she was nominated for the Golden Globe Award for New Star of the Year – Actress. For playing a woman in a difficult marriage in the drama film Twice in a Lifetime (1985), she earned a nomination for the Academy Award and Golden Globe Award for Best Supporting Actress. She has also acted in Love Letters (1984), Alamo Bay (1985), Nowhere to Hide (1987), Uncle Buck (1989), Field of Dreams (1989), Female Perversions (1996), Pollock (2000), and Gone Baby Gone (2007). After a lack of "meaningful roles", she gained newfound attention for her performance in the horror film Weapons (2025).
On television, Madigan portrayed Sarah Weddington in the television film Roe vs. Wade (1989), for which she won the Golden Globe Award and was nominated for a Primetime Emmy Award. She also took roles in the HBO series Carnivàle (2003–2005), Grey's Anatomy (2008–2009), and Fringe (2009). On stage, she has acted in the Off-Broadway production of The Lucky Spot (1987), for which she was nominated for the Drama Desk Award for Outstanding Actress in a Play, and a 1992 Broadway production of A Streetcar Named Desire in the role of Stella Kowalski.
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Filmography
Cast Credits

Rebuilding
Character: Bess
MOVIE • 2025

Weapons
Character: Gladys
MOVIE • 2025

Brooklyn, Minnesota
Character: Gail
MOVIE • 2024

Bull Street
Character: Mary-Ann
MOVIE • 2024

Go For Grandma
Character: Grandma
MOVIE • 2023

Antlers
Character: Principal Booth
MOVIE • 2021

Penny Dreadful: City of Angels
Character: Miss Adelaide Finnister
TV • 2020

The Hunt
Character: Ma
MOVIE • 2020

The Last Full Measure
Character: Donna Burr
MOVIE • 2020

Stuck
Character: Sue
MOVIE • 2019

A Crooked Somebody
Character: Joyce Vaughn
MOVIE • 2018

American Woman
Character: Peggy
MOVIE • 2018

American Socialist: The Life and Times of Eugene Victor Debs
Character:
MOVIE • 2018

Grey Lady
Character: Lola
MOVIE • 2017

Buried Child
Character: Halie
MOVIE • 2016

Rules Don't Apply
Character: Mrs. Bransford
MOVIE • 2016

Ice
Character: Diane Pierce
TV • 2016

Sensitivity Training
Character: Nancy
MOVIE • 2016

Grace and Frankie
Character: Elaine
TV • 2015

How to Get Away with Murder
Character: Irene Crawley
TV • 2014
Crew