Strike the Blood

Itogami Island is a manmade island in the middle of the Pacific Ocean where summer never ends. A high school student at Saikai Academy, Akatsuki Kojou, is on his way home from studying with his classmates, Aiba Asagi and Yaze Motoki, when he notices a girl in the Saikai Academy middle school uniform following him.

Yukina moves into the room next to Kojou's. When Kojou sees that she only has a bare minimum of furniture and necessities, he takes her to a hardware store. Kojou's younger sister Nagisa also insists on hosting a welcome party for Yukina, adding up to a very lively day.

The morning after the battle against the Combat Deacon and his homunculus, the town is left in ruins. Yukina had been shocked to see how vastly Kojou's power exceeded that of the Familiar, but now she learns that Kojou can't even control his own Familiars. Kojou and Yukina pursue the escaped Eustach and Astarte to an abandoned laboratory, where another intense battle awaits them...

Eustach and Astarte continue their assault, finally launching an attack on the central support of the manmade island. When Kojou learns that Asagi is trapped inside, he's eager to save her, but his inability to control his own Familiars holds him in place. Unable to see him go on like this, Yukina makes a suggestion he never expected...

It's nearly time for the Saikai Academy ball sports tournament, and Yukina and Nagisa are all fired up to act as cheerleaders! And thanks to the workings of Motoki and Rin, Kojou and Asagi are paired up to participate in the badminton doubles match for their class. Meanwhile, Natsuki is occupied with the capture of some therianthropes that have appeared in the warehouse district, and someone is targeting the Fourth Progenitor again...

Kojou and Yukina meet Dimitrie Vatler, a nobleman who shows an abnormal degree of affection toward the Fourth Progenitor, and Kirasaka Sayaka, Yukina's old friend also under the employ of the Lion King Organization. When Vatler proposes that Kojou capture some terrorists hiding out on Itogami Island and Yukina volunteers to take care of them instead, Vatler challenges Yukina to test her suitability for the task. And, though Sayaka has always been a friend of Yukina's since childhood, her behavior starts to change...

Blue Elysium, a new fantasy marine resort, is holding its trial opening and Motoki wants the gang there. Kojo and Asagi end up working a yakisoba booth while Yukina and Nagisa see the sights. Elsewhere on the grounds, Sayaka rescues Yume Eguchi, a younger girl abductee but after giving the girl a photo of Kojo and sending her ahead to the lifeguard centre, is herself taken prisoner by a mysterious sword shaman

Kiriha Kisaki, who works for the Taishikyoku, an agency similar to and in competition with the Lion Kings, offers to release Sayaka once her mission is complete. Until then Sayaka will be put to work. Kojo discovers that Yume is a succubus demon, and her ostensible sister Riru is actually her own alter ego, concocted to cope with past trauma. The others all rise under her mischievous control and make advances upon Kojo.

While Asagi investigates, she is interrupted by Lydianne Didier, who reveals that she is working for the Taishikyoku, managing the LYL program and will protect their systems against all comers. She challenges Asagi to hacking combat and begins her attack. Lilith's spirit awakens early and automatically, contrary to Kazuomi's schemes.

Yukina stalks Kojo as he plays with Yume. A stranger approaches and while chatting her up, half-jokingly accuses her of stalking. He is Gajou, the father of Kojo and Nagisa. Soon after, he leaves the island with Nagisa. On New Year's Eve, Yukina exploits Nagisa's absence to play house with Kojo in his apartment. Motoki arrives with Yume, Kanon, Astarte and Asagi and all visit the temple together. A cryptic message from Nagisa arrives with only a photo of a magic circle in the sky.

Natsuki magically prevents Kojo from leaving her premises. Kanon recruits Nina to spring him. Outside, Kiriha offers Yukina and him a private jet and false travel documents. Her agency is having fun at the expense of the rival Lion Kings. Asagi continues her efforts to leave the island with Mogwai's aid. Lydianne assists, and later the convict Meiga.

Gajou and Nagisa arrive at the temple at Lake Kannawa. He is captured and his jailers are two Lion King miko, Yuiri Haba and Shio Hikawa. Plans for dealing with the sealing relic known as 'Avalon' are discussed. Shirona Kuraki of the Lion Kings will conduct the ritual involving Nagisa, supported by Yuiri. A side-effect of the ritual will permanently expunge the remnant of Avrora from Nagisa.

Strange occurrences at sea result in Itogami Island becoming isolated. Nagisa continues to suffer effects from her previous exertions. A terrorist group known as Tartarus Lapse begins operations on the island.

The terrorists launch an attack upon the warehouse district. Afterward, Kojo and Himeragi meet the terrorist leader, Senga Takehito, who tries to recruit them. He reveals his beliefs about the true nature of the island, its purpose of reviving Cain, and his plans to oppose this.

At Mogwai’s urging and with Motoki’s assistance, Asagi makes her way to the Keystone Gate in order to end the hacking attack upon the island’s network. Meanwhile, Kojo and Himeragi battle ineffectively against the demons unleashed by the terrorists.

After the terrorist incident on Itogami Island, Kojo and the others are helping with the Island's recovery. On the other hand, Asagi, who gained popularity with the public for preventing hacking in the past incident, works as an ambassador for revival activities for the Island Management Corporation. However, Kojo feels like something is off when he sees Asagi on the big screen.

Kojo and the others go to rescue Asagi, who was imprisoned on the 0th floor of the Keystone Gate. Kojo is worried about Himeragi's poor condition, but Himeragi goes with Kojo nonetheless. What was waiting for Kojo and Himeragi on the 0th floor?

Kojo and the others are helpless by the power of Meiga Itogami's Cleansing ability. Kojo wonders what the hell this Cleansing ability is. At that time, the truth about the Cleansing is passed on to Kojo. Will Kojo be able to protect Himeragi and Itogami Island from Meigawa Itogami?!

Kojo is preparing to enter the Node and rescue Avrora, but the MAR, Led by the sister of the director Shahryar Ren, Radori Ren, intervenes. With the threat of a Tenbu ancient flying fortress, Radori claims she wants to prevent a war and demands that the Itogami Island be sold to the MAR.

Yukina is sent by the Lion King Organization to the bottom of the Keystone Gate to destroy the kagame stone, the keystone of the entire island, to sink Itogami Island and close the Node portal. While she hesitates to use the Sekkarou to complete her task, Kojo arrives to stop her, determined to fight to defend the island.

Radori Ren tries to show the strength of the Dantou Familiar to Kojo and the others by destroying Tokyo. Meanwhile La Foria who leads the fleet of Knights of the Second Coming attacks Shito (Carena City).

Kojo enters the Node with Yukina to Stop Shahryar Ren and rescue Avrora.